Cachexia is a multifaceted condition characterized by persistent muscle loss that cannot be completely remedied through standard nutritional support, resulting in a decline in physical function. This condition can be masked by excessive weight, obesity, fluid retention, or tumor mass. Anorexia, which indicates a reduced appetite, is commonly observed in cancer patients, although its precise frequency remains unclear.
When cachexia is primarily caused by diminished food intake, it is referred to as cancer-related cachexia and anorexia syndrome (CACS), which encompasses muscle wasting, fat breakdown, and reduced dietary consumption, distinguishing it from simple cachexia.
Some researchers propose that cannabis from Daily Marijuana Canada could enhance appetite and alleviate nausea in cancer patients.
Table of Contents
Key Takeaways:
- THC capsules from Daily Marijuana Canada may assist cancer patients in increasing their food intake and reducing sickness, thereby enhancing their quality of life.
- Studies suggest that cannabis interacts with brain cells that regulate hunger, potentially aiding appetite challenges in cancer patients and others.
- THC capsules are reliable, user-friendly, discreet, and have prolonged effects, making them suitable for medical marijuana users who prefer not to smoke.
Cancer Cachexia and Anorexia Syndrome
Cachexia is a condition associated with substantial weight loss due to the depletion of muscle and fat, frequently observed in individuals with severe illnesses such as heart failure, HIV/AIDS, COPD, kidney failure, and particularly cancer.
This condition typically occurs alongside anorexia, which is characterized by a decreased appetite leading to a minimum of 5% weight loss. Together, they constitute cancer anorexia-cachexia syndrome (CACS).
Hospitalized cancer patients often exhibit poor dietary intake, with nearly half being malnourished or at risk of malnutrition. Cachexia not only compromises patients’ quality of life but also interferes with treatment and can hasten the end of life. Its incidence increases significantly as death approaches, with cachexia identified as a leading cause of death in over 20% of cases.
Despite its common occurrence, CACS frequently goes undetected and untreated in clinical environments due to the absence of clear definitions, diagnostic standards, classification systems, and approved treatments. Clinicians evaluate a patient’s nutritional status through various parameters, including body weight, skin fold thickness, and mid-arm circumference, though body weight is predominantly relied upon, often using inappropriate reference weights.
Treatment
The most evident approach to address anorexia is to enhance nutrition, although evidence supporting its efficacy is limited. For cancer patients, nutritional care typically involves:
- Dietary Counseling
- Oral Supplements
- Enteral and Parenteral Nutrition
However, the success of these interventions varies based on the type and stage of cancer.
Pharmacological Approaches
Currently, no verified medications exist for treating Cancer Anorexia-Cachexia Syndrome (CACS), though some drugs are utilized off-label or are under clinical investigation. These medications can be categorized into four groups based on their mechanisms:
- Appetite Stimulants
- Cytokine Modulators
- Anabolic Agents
- Combination Therapies
Additionally, megestrol acetate, a progestin, is employed separately due to its unclear mechanism of action.
Cannabis in Medicine
The cannabinoid could enhance the lives of cancer patients and pave the way for future treatments. This presents hope for those suffering from cachexia, a condition characterized by appetite loss and malnourishment. It offers relief without intoxicating effects, positioning it as a potential remedy for these patients.
Various cannabis formulations with different effects are available, including inhaled THC for rapid onset and short-lived effects, and orally ingested THC for slower absorption and prolonged effects. Sublingual administration provides a quick onset lasting 2 to 4 hours.
Clinical Trial
A study by researchers from Israel and the United States evaluated how cannabis pills affect CACS in advanced cancer patients. This discovery significantly impacts the treatment of appetite disorders faced by cancer patients, individuals with anorexia, and possibly those with obesity.
Methods
The study utilized cannabis capsules containing two types of oil-based compounds, aimed at administering 10 mg doses twice daily for six months, comprising 9.5 mg of tetrahydrocannabinol (THC) and 0.5 mg of cannabidiol (CBD).
Should participants encounter side effects, the dose was reduced to 5 mg twice daily (4.75 mg THC and 0.25 mg CBD). Weight measurements were taken at each doctor’s appointment, aiming for participants to gain at least 10% more than their initial weight.
Results
Out of 24 patients who consented to participate, 17 began treatment with cannabis capsules. However, only 11 continued for over two weeks. By the study’s conclusion, 3 out of 6 patients who completed the treatment achieved the primary goal of a 10% weight gain. The weight of the remaining three patients remained unchanged.
Tumor necrosis factor-α (TNF-α), an inflammation marker, decreased following treatment. Patients reported improved appetite and mood, along with reduced pain and fatigue.
Despite several challenges, this initial study indicated a weight gain of 10% or more in 3 out of 17 patients (17.6%) using daily doses of 5 mg once or twice without significant side effects. These findings support the need for a larger, more controlled study on cannabis capsules for patients with CACS.
Cannabis Capsules
If you enjoy edibles, cannabis flower, or classic pre-rolls, exploring new ways to experience cannabis is always thrilling.
THC capsules represent one of the latest innovations in the cannabis market. These capsules are cannabis pills containing a specific dose of THC, derived from concentrated cannabis extracts mixed with a neutral oil. They resemble cannabis tinctures in capsule form (also termed cannabis oil capsules or THC pills).
Key Components
- Cannabis Extract: This concentrated extract is obtained from the cannabis plant using a method selected by the manufacturer. THC capsules are rich in THC, though some may contain only CBD or varying CBD/THC ratios.
- Neutral Oil Suspension: THC is not water-soluble, hence it is suspended in an oil for optimal absorption by the body. Common oils include medium-chain triglycerides (MCT oils), promoting digestion and absorption.
Benefits
Medical marijuana patients and recreational users alike can gain from cannabis capsules. They provide:
- Convenience: Consuming a cannabis capsule is as straightforward as taking any other oral supplement. Simply swallow it with water, with no fuss.
- Precision Dosage: For medical users, having precise control over cannabinoid intake is crucial for achieving desired effects. With THC capsules, each dosage is measured, eliminating uncertainty.
- Smoke-Free Option: Many prefer to avoid smoking or vaping due to personal choices or health considerations. THC capsules present a smoke-free alternative, suitable for those with respiratory concerns.
- Longer Effects: Capsules typically deliver longer-lasting effects compared to smoking or vaping, making them ideal for extended relief from symptoms over several hours.
Cannabis Capsules vs. Other Forms of Medicinal Cannabis
| Aspect | Cannabis Capsules | Other Forms of Medicinal Cannabis |
| Dosing | Precise dosing with each capsule | Dosing may vary depending on the method of consumption (e.g., smoking, vaping, edibles) |
| Consumption | Oral ingestion | Smoking, vaping, edibles, tinctures |
| Effects | Longer-lasting, gradual onset | Immediate onset, shorter duration |
| Effects on Appetite Stimulation | Gradual stimulation | Immediate stimulation |
Place a Medical Cannabis Delivery Order Conveniently
With the surging demand for dependable cannabis delivery services, online dispensaries provide a convenient solution. From same-day delivery to premium cannabis products, these dispensaries offer a broad selection to meet every preference and requirement.
If you’re in search of cannabis flower, pre-rolls, edibles, or vape pens, you can easily explore Daily Marijuana Canada’s top cannabis offerings from the finest marijuana plants. Shop for your preferred THC products comfortably from home.
So why hesitate? Experience same-day delivery today.
Frequently Asked Questions
What are the different types of capsules?
One additional benefit of cannabis pills/capsules is their versatility – manufacturers can create various capsule types for consumers to select from. This allows you to find capsules that align with your personal preferences.
- 1:1 Capsules: These capsules deliver an equal ratio of THC to CBD in each dose, available with sativa or indica strains in various concentrations like 5 mg, 20 mg, 50 mg, or 100 mg cannabinoids per capsule.
- 3:1 Capsules: These capsules provide a ratio of 3 parts CBD to 1 part THC in each dose.
- THC Capsules: These capsules contain THC exclusively, with varying concentrations per capsule, formulated from different Sativa or Indica strains for specific effects.
- CBD Capsules: These contain only CBD, with no THC, therefore they do not induce mind-altering effects. They are intended for individuals seeking the benefits of CBD alone.
How do capsules interact with your body?
- The outer shell of the capsule disintegrates in your digestive system after consumption.
- The contents of the capsule are absorbed into the bloodstream.
- THC (and other cannabinoids) undergo metabolism in the liver.
How long does it take for cannabis capsule effects to kick in?
Typically, THC capsules take around 90 minutes to begin showing effects. The effects can last between 5 to 12 hours, gradually diminishing in intensity. Compared to inhaled cannabis, capsule effects generally last twice as long on average.
However, experiences may vary based on factors like age, medications, personal cannabis tolerance, and cannabinoid composition. Some users also report differing effects depending on specific cannabinoids present, potentially due to the “entourage effect.”
How to mail order marijuana?
To mail order recreational cannabis, seek a reliable delivery service online that supplies high-quality cannabis products. After selecting your items, choose “order cannabis delivery,” and a delivery driver will securely bring your order. Ensure the service is trustworthy for a smooth purchasing experience.
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